Overview of TB-500
TB-500 (Ac-LKKTETQ) is a synthetic heptapeptide corresponding to the N-acetylated active fragment of Thymosin Beta-4 (Tβ4), a highly conserved actin-sequestering protein found in almost all mammalian cells. In laboratory and in-vitro environments, the sequence has been studied extensively for its role in cellular dynamics, particularly its ability to bind to cellular actin.
By modulating actin polymerization, TB-500 is observed to facilitate rapid cell migration—a foundational process in cellular repair and regeneration models. Current research applications focus on its potential to influence angiogenesis (the formation of new blood vessels), mitigate inflammatory pathways, and support the accelerated regeneration of muscle, tendon, and endothelial tissues in isolated research models.
Research Applications:
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Actin Regulation: Investigating the modulation of actin polymerization and its direct effect on cellular mobility.
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Angiogenesis Models: Observing the promotion of new blood vessel formation in damaged or hypoxic tissue samples.
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Tissue Repair Studies: Analyzing cellular responses in muscle, ligament, and dermal repair assays.
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Inflammatory Pathway Modulation: Researching its cytoprotective properties and downregulation of inflammatory cytokines.
The Secra Labs Quality Guarantee
This product has been synthesized to the highest clinical standards. Every batch of Secra Labs TB-500 undergoes rigorous independent HPLC and MS testing to ensure a minimum purity threshold of 99%, guaranteeing highly stable, reproducible results for your laboratory assays.
Disclaimer: This product is sold strictly for in-vitro laboratory research, development, and analytical purposes. It is not a drug, cosmetic, or food additive. It has not been evaluated by the FDA and is strictly prohibited from human or animal consumption, injection, or dosing.
Other Details / Product Specifications
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Synonyms: Thymosin Beta-4 Fragment, Ac-LKKTETQ
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CAS Number: 885340-08-9
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Molecular Formula:C38H68N10O14
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Molecular Weight: 889.02 g/mol
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Sequence: Ac-Leu-Lys-Lys-Thr-Glu-Thr-Gln
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Appearance: White lyophilized solid
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Storage Guidelines: Store lyophilized powder at -20°C for long-term preservation. Keep away from direct light and moisture.
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Reconstitution: Researchers should refer to standard laboratory protocols for peptide reconstitution and buffering. (Secra Labs does not provide reconstitution guidelines).







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